13
3
30
Cat. No. | Product Name | Target | Signaling Pathways |
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TP1819L |
Substance P 1-9 aceate
|
Neurotensin Receptor | GPCR/G Protein |
Substance P 1-9 aceate 是九肽,可减少豚鼠回肠和膀胱对 P 物质的失活。 | |||
TP1819 |
Substance P (1-9)
|
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Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons. | |||
T63122 | CBP/p300-IN-19 | ||
CBP/p300-IN-19 是一种 p300/CBP HAT 的有效抑制剂,能够作用于 p300-HAT (IC50: 1.4 μM)、CBP-HAT (IC50: 2.2 μM)、PCAF (IC50>100 μM)、Myst3 (IC50>100 μM)。CBP/p300-IN-19 具有抗肿瘤活性。 | |||
T63565 | CBP/p300-IN-19 hydrochloride | ||
CBP/p300-IN-19 hydrochloride 是选择性的、有效的 p300/CBP HAT 抑制剂,能够作用于 p300-HAT (IC50: 1.4 μM)、CBP-HAT (IC50: 2.2 μM)、PCAF (IC50>100 μM)、Myst3 (IC50>100 μM)。CBP/p300-IN-19 hydrochloride 具有抗肿瘤作用。 | |||
T8533 |
ML318
|
Others; Antibiotic | Microbiology/Virology; Others |
ML318 是 PvdQ 酰基转移酶的联芳基腈抑制剂,可以结合在酰基结合位点上,IC50为 20 nM。它抑制铜绿假单胞菌的 IC50为 19 μM。它可防止嘧啶的产生并限制了铜绿假单胞菌在铁限制条件下的生长。 | |||
T80285 |
KAMP-19
|
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KAMP-19,一款角蛋白衍生的抗菌肽,展示出对铜绿假单胞菌 (P. aeruginosa) 的有效抗菌作用。 | |||
T63267 |
P-gp/BCRP-IN-1
|
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P-gp/BCRP-IN-1 (compound 19) 是一种潜在的、相对安全的、口服有效的外排转运蛋白(P-gp 和 BCRP) 抑制剂。P-gp/BCRP-IN-1 通过抑制 P-gp 和BCRP 的外排功能产生耐药性逆转,P-gp/BCRP-IN-1可克服紫杉醇的耐药性,提高紫杉醇的口服生物利用度。 | |||
T75067 | Antimalarial agent 19 | Parasite | Microbiology/Virology |
Antimalarial agent 19(compound 6e)是一种活性抗疟疾化合物,对K1型恶性疟原虫和伯氏疟原虫展现出较强的抑制效果,其EC50值分别为0.3 µM和15.3 µM。相较于γ-肝硫平,该化合物具有更好的水溶性、肠道渗透性以及微粒体稳定性。 | |||
T62737 |
KRAS inhibitor-15
|
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KRAS inhibitor-15 (compound 3-19) 是一种 KRAS G12C 的有效抑制剂 (IC50: 0.954 μM)。KRAS inhibitor-15 在 MIA PaCA-2,A549 细胞中表现出 p-ERK 抑制作用,IC50s 分别为 2.03,>33.3 μM。KRAS inhibitor-15 具有潜力进行胰腺癌、结直肠癌和肺癌的研究。 | |||
T38276 |
Benzomalvin C
|
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Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/ml in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 μM for recombinant IDO. It was isolated from Penicillium and contains an epoxide group at C-19 and C-20, which is not present in benzomalvins A, B, or E. | |||
T61643 |
Vonoprazan hydrochloride
|
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Vonoprazan hydrochloride 是一种高效且具口服活性的质子泵抑制剂 (PPI) 和钾竞争性酸阻断剂 (potassium-competitive acid blocker, P-CAB),展示出优秀的抗分泌活性。在 pH 为 6.5 的条件下,该化合物可抑制猪胃微粒体内 H+,K+-ATPase 的酶活性,呈现出 19 nM 的 IC50 值。Vonoprazan hydrochloride 主要应用于胃酸相关疾病的研究,包括胃食管反流病和消化性溃疡,并可用于根除幽门螺杆菌。 | |||
TP1052 |
Protein Kinase C (19-31) (TFA)(121545-65-1,free)
PKC (19-31) (TFA),Protein Kinase C (19-31) (TFA) |
||
Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate p | |||
T36666 |
Dehydro Warfarin
|
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Dehydro warfarin is a metabolite of (±)-warfarin .1It is formed from (±)-warfarin by rat liver microsomes. 1.Kaminsky, L.S., Fasco, M.J., and Guengerich, F.P.Comparison of different forms of liver, kidney, and lung microsomal cytochrome P-450 by immunological inhibition of regio- and stereoselective metabolism of warfarinJ. Biol. Chem.254(19)9657-9662(1979) |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3283 | 8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate | Others | Others |
8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3283,CAS号为 117254-98-5。 | |||
TN6287 |
Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside
Anisofolin B |
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Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6287,CAS号为 1448779-19-8。 | |||
T38262 |
Sphingosine (d14:1)
|
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Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04874 |
IL-23 P19/IL23A Protein, Human, Recombinant (hFc)
IL-23A,IL-23,interleukin 23, alpha subunit p |
Human | HEK293 Cells |
IL-23 P19/IL23A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is Q9NPF7. | |||
TMPY-00406 |
IL-23 Protein, Human, Recombinant (His)
IL23P19,P19,SGRF,IL-23,I... |
Human | HEK293 Cells |
IL-23 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is NP_002178.2&NP_057668.1. | |||
TMPY-05247 |
IL-23 Protein, Human, Recombinant (His), Biotinylated
IL23P19,IL23,P19,IL-23A,... |
Human | HEK293 Cells |
IL-23 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is NP_002178.2&NP_057668.1. | |||
TMPY-05648 |
IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated
IL23,IL-23,白细胞介素,白介素,P19,IL23P |
Human | HEK293 Cells |
IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 57.6 kDa and the accession number is NP_002178.2&NP_057668.1. | |||
TMPY-02215 |
Coagulation factor IX/F9 Protein, Human, Recombinant (His)
FIX,PTC,Coagulation factor 9,coagulation factor IX,... |
Human | HEK293 Cells |
Coagulation factor IX/F9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is AAB59620.1. | |||
TMPY-04987 |
IL-23 P19/IL23A Protein, Human, Recombinant (mFc)
IL-23,interleukin 23, alpha subunit p1... |
Human | HEK293 Cells |
IL-23 P19/IL23A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9NPF7. | |||
TMPK-01169 |
IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated
Interleukin-23 subunit α,Interleukin-23 subunit alp... |
Mouse | HEK293 Cells |
The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma. | |||
TMPY-05355 |
Coagulation factor IX/F9 Protein, Human, Recombinant (hFc)
P19,Coagulation factor 9,HEMB,FIX,THP<... |
Human | HEK293 Cells |
Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.5 kDa and the accession number is P00740-1. | |||
TMPY-02495 |
p19 INK4d Protein, Human, Recombinant (GST)
p19-INK4D,INK4D,cyclin-dependent ... |
Human | E. coli |
Cyclin-dependent kinase inhibitor 2D(also known as CDKN2D or p19ink4d), a member of the INK4 family of cyclin-dependent kinase (CDK) inhibitors, negatively regulates the cyclin D-CDK4/6 complexes, which promote G1/S transition by phosphorylating the retinoblastoma tumor-suppressor gene product. It is clearly shown that DNA repair is the main target of p19ink4d effect and that diminished apoptosis is a downstream event. Experiments has uncovered a role of p19INK4d as a regulator of DNA-damage-ind... | |||
TMPJ-01100 |
UBE2V1 Protein, Human, Recombinant (His)
TRAF6-Regulated IKK Activator 1 Beta Uev1A,P/OKcl.<... |
Human | E. coli |
Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inactive on its own. However, in the cytoplasm UBE2V1 is able to form a catalytically active complex with UBE2N/Ubc13, which mediates the synthesis Lys63-linked Ubiquitin chains and is required for NF-kappa B activation. UBE2V1 is required for UBE2N (Ubc13)/UBE2V1 Complex-dependent Ly... | |||
TMPY-01335 |
REG1A Protein, Human, Recombinant (His)
regenerating family member 1 alpha,P19... |
Human | HEK293 Cells |
REG1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P05451. | |||
TMPY-05474 |
REG1A Protein, Human, Recombinant (His), Biotinylated
PSPS,R EG,PSPS1,MGC12447... |
Human | HEK293 Cells |
REG1A Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P05451. | |||
TMPH-00779 |
IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)
|
Guinea pig | E. coli |
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible fo... | |||
TMPY-06269 |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & L452R & E484Q & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & L452R & E484Q & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.62 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06259 |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & L452R & E484Q & D614G & P681R, His & Avi), Biotinylated
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & L452R & E484Q & D614G & P681R, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 78.43 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06417 |
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.22 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06286 |
SARS-CoV-2 Spike S1+S2 Protein (T19R & L452R & E484Q & D614G & P681R & D950N & G142D, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (T19R & L452R & E484Q & D614G & P681R & D950N & G142D, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.55 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06252 |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.27 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06444 |
SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.23 kDa and the accession number is YP_009724390.1. | |||
TMPY-06412 |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.56 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06289 |
SARS-CoV-2 Spike S1+S2 Protein (T19R & L452R & E484Q & D614G & P681R & D950N & G142D, His & Avi), Biotinylated
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (T19R & L452R & E484Q & D614G & P681R & D950N & G142D, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 136.36 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06267 |
SARS-CoV-2 Spike S1 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R, His & Avi), Biotinylated
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 78.09 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06432 |
SARS-CoV-2 Spike S1+S2 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.14 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06415 |
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R & D950N, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.49 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06413 |
SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.28 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06272 |
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.20 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06288 |
SARS-CoV-2 Spike S1+S2 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R & D950N, His & Avi), Biotinylated
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R & D950N, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 136.01 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06443 |
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.29 kDa and the accession number is YP_009724390.1. | |||
TMPY-06437 |
SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.20 kDa and the accession number is A0A6G7K2L4. | |||
TMPJ-01277 |
CRT2 Protein, Human, Recombinant
CALR3,Calreticulin-3,calreticulin-2,calsperin,CRT2 |
Human | E. coli |
Calreticulin-3 belongs to the calreticulin family, members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain, a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. During spermatogenesis process, Calreticulin-3 may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Defects in CALR3 are the cause of familial hypertrophic cardiomyopathy t... |